Soothing Vulva Cream

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Soothing Vulva Cream

Our Soothing Vulva Cream is a gentle topical cream designed to relieve external burning, dryness and irritation without hormones.

Formulated with prescription-grade hyaluronic acid, aloe, and vitamin E, our Soothing Vulva Cream is packed with ingredients shown in clinical studies to soothe and moisturize — in some cases just as well as estrogen — but without the hormones.

Can be used alongside our Hyaluronic Acid Suppositories for complete moisture support.

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30 doses (6 gram tube)

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$29

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Ingredients

5mg hyaluronic acid, aloe vera, Vitamin E, Vitamin A Palmitate, hypoallergenic cream base, Ethoxy

Allergens: aloe vera, corn

How to Use

Apply 4 clicks of cream onto the external vulvar area as needed, up to 3 times per week.

Do not use inside the vagina. Use within 180 days of purchase.

Quality & Safety

At Evvy, we’re committed to giving you the safest, most effective care—so we use only prescription-grade, non-toxic ingredients that are free from harmful additives.

Non-Toxic
No PFAs
No Parabens
No BPAs
No Phthalates
No GMOs
No Sulfites
No Artificial Colors/Fragrances/Dyes

Please note that our Rx Symptom Relief products can help manage symptoms, but are not being prescribed to treat an underlying condition. They are ideal for use alongside Evvy’s vaginal microbiome test and Complete Treatment Programs, which can help uncover and target the root causes of symptoms.

This is a compounded medication, formulated in a 503a NABP-accredited pharmacy. Compounded products are not approved by the FDA.

Eligibility

Your specific prescriptions will be determined at the sole discretion of an Evvy-affiliated provider. To ensure safe, compliant, and personalized care, we cannot prescribe this treatment for patients who are:

Pregnant
Breastfeeding
Younger than 18 or older than 80 years old

This treatment is not yet available in Canada or the following US states: Arkansas, Delaware, Kansas, Kentucky, Mississippi, New Mexico, Puerto Rico, Rhode Island, South Carolina, Vermont, US Virgin Islands, Washington DC, West Virginia, Armed Forces Europe / Pacific

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science-backed formulations

Prescription-grade ingredients

clean & non-toxic

No harsh additives or irritants

Why Soothing Vulva Cream

Gently soothe dryness & irritation

Soothe external irritation and inflammation

Gently repair with targeted ingredients safe for sensitive skin

Replenish hydration for long-lasting comfort

Why our formulation

Gentle yet effective, even for sensitive skin

Hyaluronic Acid

Delivers advanced hydration

Prescription-grade hyaluronic acid binds up to 1,000 times its weight in water, deeply hydrating vaginal tissue to relieve dryness, itching, and irritation without hormones. In multiple clinical studies, hyaluronic acid was generally found to be effective in improving vulvovaginal symptoms like painful sex, itching, burning, vaginal dryness, pH balance and atrophy.

Pure Aloe

Soothes irritation

Aloe is both an antioxidant and an anti-inflammatory, making it the perfect addition to our soothing formulation. Research shows aloe can be as effective as estrogen for relief of vaginal dryness.

Vitamin E

Improves vaginal elasticity

Vitamin E has been shown to improve symptoms by supporting blood flow and keeping blood vessels flexible. This can increase blood flow which boosts the overall health and moisture of vaginal tissues.

Backed by science & designed by OB-GYNs

From studies of the same active ingredients on post-menopausal women:

76%

reported fewer symptoms after Vitamin E (Emamverdikhan 2016).

84%

reported an improvement in vaginal dryness after hyaluronic acid (Chen 2013).

86%

reported less vaginal itching and burning after hyaluronic acid (Chen 2013).

How It Works

Step 1

Order your Rx from Evvy

All Evvy prescription (Rx) products are custom compounded at a 503a NABP-accredited pharmacy, ensuring clean and safe ingredients.

Step 2

Complete your intake form

A licensed, Evvy-affiliated provider will review your order and intake form within 24 hours. We’ll reach out to you over email if there are any questions.

Step 3

Rx shipped to your door

If prescribed, your prescriptions will be shipped straight to you and typically arrive within 3-6 business days.

Step 4

Test with Evvy for root cause

Evvy’s products are designed to relieve symptoms, not treat underlying conditions. Taking an Evvy test gives you a complete picture of your vaginal health and empowers you to address root causes, not just symptoms.

From the community

Providers and patients choose Evvy

“The formulation for Evvy’s Soothing Vulva Cream is as gentle as it is effective, offering hormone-free comfort for even the most sensitive skin. With clean, pure ingredients like hyaluronic acid and aloe, it provides safe, lasting relief from dryness and irritation.”

Dr. Kate McLean, MD, MPH, FACOG

Chief Medical Officer, Evvy

“The Hyaluronic Acid Suppositories and the Soothing Vulva Cream were all great products for me that were also a part of my treatment plan! I have used other products in the past that did nothing and even Rx that was prescribed by my OBGYN that did not help at all. Thank you so much for your help and support!! And treatment that actually helps!”

Ashley

Verified Evvy User

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FAQs for Soothing Vulva Cream

For more, visit our Help Center

What is vulva cream used for?

Vulva cream, like Evvy’s Soothing Vulva Cream, is designed to relieve external dryness, irritation, and discomfort. It’s ideal for soothing sensitive skin and providing long-lasting moisture with ingredients like hyaluronic acid, aloe, and vitamin E. By restoring hydration, Evvy’s Soothing Vulva Cream helps to reduce discomfort from everyday friction, hormonal changes, and irritation.

Where can I put vulva cream?

Evvy’s Soothing Vulva Cream is intended for use on the external vulvar area. Simply apply it to the outer skin for gentle hydration and comfort. This hormone-free, non-irritating formula is safe for sensitive skin, but it should not be applied internally.

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What is the best cream for irritated vulva?

Evvy’s Soothing Vulva Cream is an excellent choice for relieving vulvar irritation. Formulated with prescription-grade hyaluronic acid, aloe, and vitamin E, it provides fast, soothing relief from dryness and discomfort without harsh additives. With its science-backed ingredients, Evvy’s cream offers a safe and effective solution for calming and hydrating sensitive skin.

Are these treatments prescribed by a provider?

Yes, all treatments are prescribed by a provider and compounded at a 503a NABP-accredited pharmacy. If there is a mismatch between what you request and what the provider recommends, we will confirm with you before shipping.

Do these treatments require a live video or phone call with a provider?

Nope! To ensure that our customers are able to get care in a convenient and affordable way, Evvy-affiliated providers offer asynchronous consultations. This means your provider will review your results and intake without requiring a phone or video call. If your provider has any questions, we will reach out to you over email before prescribing. Research shows that there's no significant difference between async and in-person/live consultations in terms of treatment outcomes — but it's something we're looking into offering in the future for those who want it.

What's the difference between the Evvy Complete Treatment Program and Evvy's individual Rx products?

The Evvy Complete Treatment Program is only available after taking an Evvy test, and offers a fully personalized, multi-step care plan based on your unique vaginal microbiome results. It combines targeted medication, symptom relief products, and probiotics into one coordinated approach, complete with 1:1 coaching and progress tracking. This integrated program optimizes both immediate relief and long-term balance, unlike standalone Rx treatments that typically target a single symptom.

For those looking to soothe discomfort while waiting to test, Evvy’s prescription symptom relief products are a great option. These treatments offer effective relief for common symptoms like itching and dryness, making them ideal for anyone seeking comfort before diving into a more comprehensive care plan.

What is the difference between Evvy's treatments from what I can get from my doctor or what I can get over the counter?

Evvy’s treatments are formulated based on years of research plus our unique R&D on the vaginal microbiome, with insights from over 7,000 individuals to determine what truly works for vaginal health. Our treatments are prescription-grade and carefully compounded with the highest quality, non-toxic ingredients to ensure effective, targeted relief. Unlike standard treatments, Evvy’s formulations also consider the form factor and delivery method, optimizing each treatment to work safely and effectively with your body. Our platform offers a fully personalized experience, from expert-reviewed treatment recommendations to ongoing support, so you’re not just addressing symptoms—you’re actively supporting your long-term vaginal health.

We've helped 25,000+ people take control of their vaginal health

I am so thankful for Evvy’s treatment plan and guidance... Evvy’s approach felt much more comprehensive and I finally have relief after years of struggling.

Graciela

Verified Customer

Evvy actually saved my life. I couldn't be more happy with the detailed results, relevant and cutting-edge information, and immense support.

Pia

Verified Customer

The level of detail in test results is unlike anything I could ever access through my doctor’s office... and [Evvy] dramatically changed my health.

Verified Customer

For the first time since developing symptoms, I felt heard, understood, and cared for. I could cry from happiness!

Hannah

Verified Customer