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Evvy Vaginal Health Test

Get advanced insights into symptoms, fertility, and other health outcomes. Prelim results in 1-3 days.

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Bring Evvy's Cutting-Edge Vaginal Microbiome Care to Your Patients

The vaginal microbiome is a critical biomarker for female health and a leading reason women seek healthcare — yet over 50% of vaginal microbiome imbalances are misdiagnosed today. You can change that with Evvy.

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Industry leading

Vaginal Microbiome
Test & Care Platform

Get to the root cause of vaginal symptoms or uncover the microbiome’s role in fertility for your patients.

See the science

Comprehensive testing

The first and only peer reviewed, metagenomics-based vaginal microbiome test.

Evvy tests for 700+ microbes with industry leading sensitivity and specificity — providing the most reliable, comprehensive vaginal microbiome answers for vaginitis, fertility, menopause, and more in <7 days.

Evvy's test is CLIA-certified, NYS CLEP approved, and our test validation was published in the peer-reviewed Diagnostics journal. We also provide STI +PCR testing through our Expanded PCR Panel add-on.

Targeted and actionable treatment protocols

Evvy combines molecular results with patient health data to predict optimal treatments. Treatments are personalized and may include vaginal antibiotics, probiotics, estradiol, hyaluronic acid, etc. based on what's most likely to help the patient.

Our peer-reviewed study on >1k patients shows significant outcome improvements across symptom resolution, microbiome restoration, and recurrence rates — even though Evvy often sees the most complex patients.

As needed, Evvy can provide pharmacy services (ability to order and fulfill targeted Rx) and coaching through our provider and patient platform.

Trusted at scale

Evvy is trusted by over 100,000 patients and 3,000 clinicians. We have an industry leading turnaround time, with results returned in <7 days.

Through our platform, Evvy has also built the world's largest vaginal microbiome dataset — a proprietary asset unlocking more accurate diagnoses, targeted treatments, and improved outcomes at scale.

Our findings have been presented at major clinical conferences, including ACOG, ASRM, IDSOG, ISSVD, & ISSWSH.

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Industry Leading Test Accuracy¹

98%

Sensitivity

99%

Specificity
‍

¹As demonstrated in CLEP analytical validation submission

Significantly Improved Patient Outcomes2

75%

symptom resolution

50%

reduction in BV recurrence rates

60%

increase in protective bacteria

Which of your patients can benefit from Evvy?

100% Pure Boric Acid

Patients with recurrent symptoms and infections

There are many reasons why patients experience recurrent vaginal symptoms and infections – from misdiagnoses (an estimated 61% of BV and 77% of yeast infection diagnoses are incorrect), to co-infections, to poor re-colonization of the microbiome, and more.

At Evvy, our goal is to to break the cycle of symptoms and infections through better testing, treatment, and education. We start with our comprehensive test that screens for 700+ microbes to catch things traditional tests like cultures, wet mounts, and PCR, miss. We then combine those molecular results with the patient's health history to deliver the optimal treatments for each patient.

Patients who are trying to conceive

Patients who are trying to conceive

Research associates a healthy vaginal microbiome with improved fertility outcomes — across natural fertility, IVF, and IUI (Vitale et al, 2021).

Evvy’s Vaginal Health Test includes access to our proprietary Fertility Insights, including four Microbiome Markers associated with fertility outcomes — Protective Score, Diversity Score, Fertility Disruptors, and STI Status — alongside the optimal ranges based on the latest research.

Beyond testing, we provide step-by-step guidance on restoring your patient’s vaginal microbiome, helping to promote a healthy environment for conception.

100% Pure Boric Acid

Patients navigating perimenopause or menopause

Shifts in estrogen during perimenopause and menopause can impact the vaginal microbiome and contribute to genitourinary syndrome of menopause (GSM) — one of the leading symptoms of menopause.

As estrogen declines, the glycogen that feeds protective Lactobacillus also declines, making it harder for those bacteria to thrive. This change results in increased vaginal pH, increased dysbiosis, and increased GSM symptoms, BV infections, and UTI risk.

Evvy takes a holistic approach to guiding treatment for vaginal symptoms in menopause by incorporating personalized microbial treatment alongside clean vaginal estradiol cream where relevant — addressing both tissue and microbial health together.

How it works

Convenient and comprehensive testing for your patients.

01

Log in to the Evvy Provider Portal.

02

Order Evvy tests in bulk or individually for your patient through the portal.

Choose the payment option that works best for you (upfront or upon activation).

03

Patient collects sample and sends it back to the lab.

Our test kits will have everything your patient needs to collect the sample and return it to our lab.

04

Results sent to both patient and provider.

Once received at the lab, Evvy returns results from the PCR add-on in 1-3 days, and from mNGS in <7 days. Results include clear interpretation and next steps.

05

Access custom, compounded formulations.

Evvy predicts the optimal ingredients and treatments based on the patient’s results, and can provide pharmacy services (prescriptions, compounding, delivery) as desired.

“Emerging research shows the vaginal microbiome’s association with fertility outcomes including implantation and pregnancy loss. Yet, this critical insight has been missing from fertility care—until now.

Evvy makes these discoveries accessible, bridging the gap between research and real-world care.”

Dr. Kate McLean, MD, MPH, FACOG

Chief Medical Advisor, Evvy

"As an OBGYN, I've seen how common and debilitating vaginal infections can be for women around the world.

As a leading researcher of the vaginal microbiome, my colleagues and I have started to uncover its role in areas beyond vaginal health — including public health challenges like STIs and HIV acquisition, infertility, preterm birth, and more.

I truly believe that Evvy's unique platform combined with the development of new therapeutics will catalyze a new era in women's health."

Dr. Craig Cohen

OB-GYN and Professor, UCSF & Evvy Advisor

"As an OB-GYN, I know how frustrating it is for both patients and clinicians to lack access to effective testing and treatments.

Evvy’s new care platform is revolutionary, and I am thrilled that patients across the country will finally have access to the best in class testing, holistic treatments, and empathetic support they deserve.”

Dr. Rebecca Nelken

OB-GYN & Female Pelvic Surgeon

Evvy has generated the world’s largest, most comprehensive dataset on the vaginal microbiome —and we’re pioneering overdue research that will transform women’s health outcomes.

Evvy is built by the world’s experts in the vaginal microbiome, women’s health and fertility.

TALK TO OUR CLINICAL TEAM
TALK TO OUR CLINICAL TEAM
Dr. Kate McLean

Dr. Kate McLean

OB-GYN + Chief Medical Advisor at Evvy
Dr. Jill Krapf

Dr. Jill Krapf

OB-GYN at Centers for Vulvovaginal Disorders
Dr. Anna Powell

Dr. Anna Powell

OB-GYN, infectious disease specialist @ Johns Hopkins
Dr. Kelle Moley

Dr. Kelle Moley

OB-GYN + VP Women's Health & Early Clinical Development @Eli Lilly and Company
Dr. Sameena Rahman

Dr. Sameena Rahman

ISSWSH Board of Directors and OB-GYN at Northwestern
Dr. Stephen Klasko

Dr. Stephen Klasko

OB-GYN + Former President and CEO at Jefferson Health
Dr. Gary Goldman

Dr. Gary Goldman

OB-GYN, pioneer in functional gynecology
Dr. Diana Currie

Dr. Diana Currie

OB-GYN & Washington Medical Commissioner
Dr. Craig Cohen

Dr. Craig Cohen

OB-GYN & Vaginal Microbiome Research-Scientist @ UCSF
Dr. Momo Vuyisich

Dr. Momo Vuyisich

PhD, Co-founder & Chief Science Officer @ Viome
Dr. Francine Camacho

Dr. Francine Camacho

PhD, Associate Director, Genomics Data Platform @ Vertex Pharmaceuticals
Prof. Londa Schiebinger

Prof. Londa Schiebinger

PhD, Hinds Professor of History of Science @ Stanford University & Director, Gendered Innovations Project
Dr. Eduardo Hariton

Dr. Eduardo Hariton

REI and SVP of Clinical Growth and Innovation @ US Fertility
Dr. David Sable

Dr. David Sable

Pioneering REI, investor, and adjunct professor
Dr. Peter Klatsky

Dr. Peter Klatsky

REI & Co-founder @ Spring Fertility
Dr. Pietro Bortoletto

Dr. Pietro Bortoletto

REI @ Terra Fertility
Dr. Paco Arredondo

Dr. Paco Arredondo

REI, Founder & Chief Medical Officer, @ PositivIVF
Dr. Lusine Aghajanova

Dr. Lusine Aghajanova

REI and Clinical Professor @ Stanford Medicine
Dr. Amber Cooper

Dr. Amber Cooper

REI & Chief Medical Officer, Genomics and Lab Operations @ Kindbody
Dr. Gaurang Daftary

Dr. Gaurang Daftary

REI & Chief Scientific Officer @ Inception
Dr. Eve Feinberg

Dr. Eve Feinberg

REI and Medical Director @ Northwestern Medicine
Dr. Sasha Hakman

Dr. Sasha Hakman

REI & Medical Director @ Beverly Hills Fertility
Dr. Roohi Jeelani

Dr. Roohi Jeelani

REI, Founder & CEO @ Onto Health
Dr. Debbra Keegan

Dr. Debbra Keegan

REI, Medical Director & VP Clinical Partnerships and Strategy @ CCRM Fertility
Dr. Sigal Klipstein

Dr. Sigal Klipstein

REI @ First Fertility
Dr. Scott Morin

Dr. Scott Morin

REI & West Coast Medical Director @ IVI RMA
Dr. Phillip Romanski

Dr. Phillip Romanski

REI and Associate Research Director @ RMA of New York (US Fertility)
Dr. Shefali Shastri

Dr. Shefali Shastri

REI & Medical Director, VP of Clinical Innovation & Education @ CCRM Fertility
Dr. Sarah Vaughn

Dr. Sarah Vaughn

REI & Chief Medical Officer @ Clair Health

Evvy’s platform is backed by 15+ peer-reviewed publications and abstracts.

Select Conferences
Select Journals
select Academic collaborators
Select REsearch
Test Methodology

A Metagenomics Pipeline to Characterize Self-Collected Vaginal Microbiome Samples

The Evvy Vaginal Health Test is now the only vaginal microbiome test in the world to be both peer-reviewed and analytically validated by CLIA, CAP and CLEP. Published in Diagnostics.

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Patient Outcomes

Remote BV Management via Metagenomic Vaginal Microbiome Testing and Telemedicine

Evvy's at-home Test & Rx Care platform is now shown in clinical research to significantly reduce symptoms and bacterial vaginosis (BV) recurrence across >1,000 patients. Published in Microorganisms.

Read More
Ongoing Prospective Clinical Study

Landmark Study Uncovering the Role of the Vaginal Microbiome in IVF Outcomes

This active study is the first-of-its-kind to use a validated, commercially available vaginal microbiome test to uncover potential microbial markers linked to IVF success. Designed with leading fertility doctors including Dr. David Sable, Dr. Peter Klatsky, & Dr. Eduardo Hariton.

Read More
BV Subtypes Whitepaper

Understanding Microbial Diversity in Bacterial Vaginosis to Improve Outcomes

Research from Evvy analyzing 15,000+ BV-diagnosed vaginal microbiomes reveals distinct microbial patterns, showing BV is a spectrum — not a single biological condition.

Read More
Retrospective Data Analysis

Microbiome-Defined BV Subtypes Are Associated With Distinct Recurrence Burden Among Participants Meeting Standard BV Criteria

mNGS profiling reveals that BV subtypes differ in reported symptoms and recurrence. This may improve interpretation of clinical variability and provide framework for subtype-specific recurrence and treatment outcomes. Presented at IDSOG (2026).

Read More
Retrospective Data Analysis

Vaginal Odor Is Associated With Increased Abundance of Prevotella, Megasphaera, Porphyromonas, and Finegoldia

‍

This study showed increasing abundance of certain species was linked to worsening odor severity, and identified the putrescine pathway in 14% of those with severe odor vs. 2% of asymptomatic individuals. It's the first study to show specific taxa associated with odor severity. Presented at IDSOG (2024).

Read More
Microbial & Genomic Science Discovery

Metabolic Network Models of the Gardnerella Pangenome Identify Key Interactions with the Vaginal Environment

Different Gardnerella species have different metabolism, which means that they will have different effects on the vaginal microbiome. Published in mSystems.

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Retrospective Data Analysis

Elevated Gardnerella Species in the Vaginal Microbiome Are Associated with Infertility in Asymptomatic Individuals

Elevated abundance of certain Gardnerella species was associated with nearly 2x higher odds of self-reported infertility among >1,000 asymptomatic testers. Presented at ACOG (2026).

Read More
Retrospective Data Analysis

Vaginal Microbiome Characteristics of Nulliparous Women Diagnosed With Infertility

The largest dataset of mNGS VMB profiles from nulliparous women with infertility found Gardnerella and Lactobacillus levels consistent with published fertility research, while providing additional insight into microbial speciation. Presented at ACOG (2025).

Read More
Retrospective Data Analysis

Characterizing the Vaginal Microbiome in Patients Attempting to Conceive for Over 12 Months: A Real-World, Metagenomic Cohort Study

Among 260 patients trying to conceive for a year or more, 91% had Lactobacillus-dominant profiles, yet disruptive anaerobes like Gardnerella were still common — suggesting that subclinical dysbiosis may influence conception. Presented at ASRM (2025).

Read More
Microbial & Genomic Science Discovery

Genome-scale metabolic network reconstruction analysis identifies bacterial vaginosis-associated metabolic interactions

Computational models of BV-associated bacteria revealed they produce caffeate, a compound that can bind estrogen receptors, when grown in the spent media of other BV-associated bacteria. This finding underscores the complex, diverse nature of BV-associated bacterial communities. Published in Nature (2025).

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Retrospective Data Analysis

Behavioral Factors Associated with the Estimated Probability of Bacterial Vaginosis in Women: A Logistic Regression Analysis of Number of Sexual Partners and Condom Use

Having one sexual partner and using condoms consistently were each linked to significantly lower odds of BV among >14,000 testers. Presented at IDSOG (2025).

Read More
Retrospective Data Analysis

Women Who Report Pain with Sex Have Varying Microbiome Profiles Based on Age

Menopausal women reporting pain with sex had more diverse, lower-Lactobacillus microbiomes than those without pain — a pattern not seen in reproductive-aged women. Presented at ISSWSH (2024).

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Retrospective Data Analysis

Co-occurrence of Candida with BV-associated bacteria and Lactobacillus

This study showed consistent co-occurrence of BV-associated bacteria with C. albicans, independent of the presence or absence of symptoms. This study underscores the importance of comprehensive microbiome profiling in the context of vaginal infections. Presented at ISSVD (2024).

Read More
Microbial & Genomic Science Discovery

Gardnerella Species Variations Show Pathogenic and Metabolic Differences

Distinct genomics differences in pathogenicity and metabolism were found across the Gardnerella genus. This variation suggests certain species may be more pathogenic than others and may be associated with different treatment outcomes. Presented at IDSOG (2023).

Read More
Retrospective Data Analysis

Incidence and Symptom Profiling of Vaginitis Containing Aerobic and Anaerobic Pathogens

Vaginitis cases involving aerobic pathogens caused more severe symptoms than anaerobic-only cases, showing symptoms alone can't reliably indicate the cause. Presented at IDSOG (2023).

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Retrospective Data Analysis

Psychosocial impact of recurrent urogenital infections: a review

This study showed consistent co-occurrence of BV-associated bacteria with C. albicans, independent of the presence or absence of symptoms. This study underscores the importance of comprehensive microbiome profiling in the context of vaginal infections. Published in Women's Health (2023).

Read More

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